BreathSpec study
Start date:December 2018 End date:
April 2019 Co-ordinated by:
Julia Grahamslaw Main trial site:
Liverpool School of Tropical Medicine
A multicentre prospective, observational, longitudinal cohort study in adult patients with suspected upper or lower respiratory infection (URTI/LRTI) to identify a spectrum of biomarkers in exhaled breath to discriminate participants with bacterial RTI from participants without.
Identification of chemical biomarkers in exhaled breath that potentially discriminates participants with bacterial RTI from participants without.
Additional endpoints explored will be variations of the chemical spectrum from all participants using a portable GC-IMS device (Breathspec) stratified by confounding factors, such as (but not limited to) gender, age, antibiotic therapy and smoking status.
Local PI
Dr Matt Reed
Director of EMERGE, Consultant, NRS Career Research Fellow & Honorary Reader in Emergency Medicine
Research Team
Fiona McCurrach
Senior Research Nurse
Julia Grahamslaw
Lead Research Nurse
Alison Williams
Senior Research Nurse
Clare Moceivei
Research Nurse- Bank Staff
Caroline Blackstock
AMU Senior Research Nurse
Sian Dalgleish
Senior Research Nurse
Dr Adam Lloyd
Honorary Research Fellow & Lecturer
Emma Moatt
Research Project Manager
More EMERGE Trials
Diagnostics devices play an important part in the clinical assessment of a patient’s health and treatment. The purpose of the study is the evaluation of a new diagnostic platform developed by LumiraDx. The evaluation is focused around various biomarkers useful in the emergency settings.
NOVEL Study
Collection of venous and capillary blood samples for the evaluation of new diagnostic devices for cardiovascular conditions
Identification and characterization of the clinical toxicology of novel psychoactive substances (NPS) by laboratory analysis of biological samples from recreational drug users.
IONA Study
Identification of Novel Psychoactive Substances (IONA)
Prospective multicentre observational study conducted over one calendar month in 2019, with the aim of describing the epidemiology of non-trauma related headache in adults presenting to emergency departments including investigations, treatments and outcome.
This will include adult patients presenting to the ED with non-trauma-related headache as their primary complaint.