Toggle menu

DEUCE

Start date:
Historic
End date:
July 2012
Co-ordinated by:
NHS Lothian

Is Rotational Thromboelastometry (ROTEM) useful to detect Occult Coagulopathy in the Emergency Department?

Aim

  • To see whether rotational thromboelastometry (ROTEM) is useful to detect occult coagulopathy in bleeding ED patients.
  • To see what proportion of patients presenting to the ED with bleeding conditions have a coagulopathy on arrival and whether this is sufficient to warrant routine ROTEM use in the ED.
  • To see what proportion of patients presenting to the ED with bleeding conditions develop a coagulopathy during their ED stay, and whether this is sufficient to warrant routine ROTEM use in the ED.
  • To see whether ED staff can be trained to use ROTEM and whether the knowledge is retained.

Trial Design

Single-centre, prospective, observational cohort study,  conducted in the Emergency Department (ED) of the Royal Infirmary of Edinburgh.

List of Publications – references

Reed MJ, Nimmo AF, McGee D, Manson L, Neffendorf AE, Moir L, Donaldson LS. Rotational thrombolelastometry produces potentially clinical useful results within 10 min in bleeding Emergency Department patients: the DEUCE study. Eur J Emerg Med. 2013; 20(3): 160-6

Chief Investigator

Dr Matt Reed

Consultant, NRS Career Research Fellow & Honorary Reader in Emergency Medicine

Local PI

Dr Matt Reed

Consultant, NRS Career Research Fellow & Honorary Reader in Emergency Medicine

More EMERGE Trials

Attitudes towards Research and Research Nurses among the clinical team in an Emergency Department (ED) and Acute Medical Unit (AMU)

Read more

Research on Research

Attitudes towards Research and Research Nurses

The study with PP100-01 in combination with NAC is designed to determine safety and tolerability of PP100-01 when co-administered with NAC as compared to the 12-hr NAC treatment regime for patients that come to the hospital after an overdose of paracetamol/acetaminophen.

Read more

The POP Trial

A Randomised Open Label Exploratory, Safety and Tolerability Study with PP100-01 in Patients Treated with the 12-hour Regimen of N-Acetylcysteine for Paracetamol/Acetaminophen Overdose

Patients commonly present to the Emergency Department with epistaxsis (nose bleed). Standard first aid measures such as applying pressure can often stem bleeding however in more severe cases of epistaxsis further treatment is required.

Read more

NoPac

Novel Use of Tranexamic Acid to Reduce the Need for Nasal Packing