This trial is a two arm, multicentre parallel group, randomised controlled, open label trial comparing intravenous levetiracetam to intravenous phenytoin for the treatment of convulsive status epilepticus (CSE) in children, young people and young adults.
The trial will run in emergency depatments in NHS secondary and tertiary hospitals in the UK, a total of 308 participants will be recruited and total study duration for each participant will be 24 hours. The Consent study will run alongside EcLiPSE and will involve parents who have been approached about the study and EcLiPSE recruiters. The study will examine approaches to recruitment and deferred consent and explore the views of parents with the aim of identifying recruitment and consent issues and potential solutions to inform EcLiPSE recruiter training materials.
Diagnostics devices play an important part in the clinical assessment of a patient’s health and treatment. The purpose of the study is the evaluation of a new diagnostic platform developed by LumiraDx. The evaluation is focused around various biomarkers useful in the emergency settings.
Collection of venous and capillary blood samples for the evaluation of new diagnostic devices for cardiovascular conditions
Evaluating the role of early CT Coronary Angiography on patients with suspected or confirmed Acute Coronary Syndrome.
Evaluating the role of early CT Coronary Angiography