HighSTEACS is a randomised controlled trial, across 10 hospitals in NHS Lothian and NHS Greater Glasgow & Clyde, assessing patient outcomes before and after the implementation of high sensitivity Troponin assay
EMERGE Research team
Cardiology Research Group
HighSTEACS is a randomised controlled trial, across 10 hospitals in NHS Lothian and NHS Greater Glasgow & Clyde, assessing patient outcomes before and after the implementation of high sensitivity Troponin assay. The primary endpoint is the one-year rate of cardiovascular death or recurrent myocardial infarction. Secondary endpoints include length of stay, unplanned coronary revascularisation, recurrent hospital admissions excluding ACS, bleeding events and non-cardiovascular death. There is also a sub-study at the ED, RIE and in one site in NHS Greater Glasgow and Clyde.
Prospective stepped wedge cluster randomised controlled trial
Patients who present to the Emergency Department with suspected heart disease
This is a study looking at incidence and risk factors for poor ankle functional recovery, and the development and progression of post-traumatic ankle osteoarthritis after significant ankle ligament injury.
SALI study - Significant Ankle Ligament Injury
The study with PP100-01 in combination with NAC is designed to determine safety and tolerability of PP100-01 when co-administered with NAC as compared to the 12-hr NAC treatment regime for patients that come to the hospital after an overdose of paracetamol/acetaminophen.
A Randomised Open Label Exploratory, Safety and Tolerability Study with PP100-01 in Patients Treated with the 12-hour Regimen of N-Acetylcysteine for Paracetamol/Acetaminophen Overdose