Toggle menu


Start date:
July 2016
End date:
March 2018
Co-ordinated by:
Main trial site:

Palpitations (noticeable pounding, fluttering or irregular heart beat) and pre-syncope (near blackout) are common Emergency Department problems sometimes due to an abnormal cardiac rhythm.

This is difficult to diagnose as clinical examination and ECG are commonly normal and symptoms have usually resolved by the time the patient arrives in the Emergency Department. Diagnosing an abnormal heart rhythm as the cause of symptoms rests on capturing it on an ECG and patients are usually discharged with advice to return to the ED again for a 12-lead ECG should symptoms recur.

The IPED study will randomise 214 consecutive patients aged 16 years or over presenting with an episode of palpitations or pre-syncope in the preceding 24 hours and whose underlying ECG rhythm during these episodes remains undiagnosed after ED assessment, to either use of a smart phone based event recorder (the AliveCor Heart Monitor and AliveECG app) or standard care.

Patients will be followed-up at 90 days. The IPED study aims to discover whether a smart phone based event recorder may allow better and earlier diagnosis of these patients, and revolutionise ED care in this area.

The IPED Study Multi-centre Sites:

Royal Infirmary of Edinburgh
Royal Berkshire Hospital
Musgrove Park Hospital
Royal London Hospital
Royal Devon and Exeter Hospital
Leicester Royal Infirmary
Derriford Hospital (Plymouth)

Chief Investigator

Dr Matt Reed

Consultant and NRS Career Research Fellow in Emergency Medicine

Research Team

Rachel O'Brien

Lead Research Nurse

Related news

Exciting new trial: SNAP40

Exciting new trial: SNAP40

10 Apr 2017 | Megan McGrath

EMERGE will soon begin recruitment to the new SNAP40 trial which will compare the new SNAP40 device with standard monitoring devices in the Emergency Department.

Read more
IPED goes large!

IPED goes large!

17 Jan 2017 | Rachel O'Brien

IPED goes large

Read more

More EMERGE Trials

Patients commonly present to the Emergency Department with epistaxsis (nose bleed). Standard first aid measures such as applying pressure can often stem bleeding however in more severe cases of epistaxsis further treatment is required.

Read more


Novel Use of Tranexamic Acid to Reduce the Need for Nasal Packing

Evaluating the kinetics of cardiac biomarkers after ST-segment Elevation myocardial infarction

Read more

HighSTEACS Bioresource

The Emergency Medicine Annotated Bioresource Consortium (EM-ABC): A pilot and feasability programme

Read more

EMERGE Biobank

Developing a bioresource for all emergency presentations