Palpitations (noticeable pounding, fluttering or irregular heart beat) and pre-syncope (near blackout) are common Emergency Department problems sometimes due to an abnormal cardiac rhythm.
This is difficult to diagnose as clinical examination and ECG are commonly normal and symptoms have usually resolved by the time the patient arrives in the Emergency Department. Diagnosing an abnormal heart rhythm as the cause of symptoms rests on capturing it on an ECG and patients are usually discharged with advice to return to the ED again for a 12-lead ECG should symptoms recur.
The IPED study will randomise 242 consecutive patients aged 16 years or over presenting with an episode of palpitations or pre-syncope in the preceding 24 hours and whose underlying ECG rhythm during these episodes remains undiagnosed after ED assessment, to either use of a smart phone based event recorder (the AliveCor Heart Monitor and AliveECG app) or standard care.
Patients will be followed-up at 90 days. The IPED study aims to discover whether a smart phone based event recorder may allow better and earlier diagnosis of these patients, and revolutionise ED care in this area.
The IPED Study Multi-centre Sites:
Royal Infirmary of Edinburgh
Royal Berkshire Hospital
Musgrove Park Hospital
Royal London Hospital
Nottingham University Hospitals NHS Trust
Chesterfield Royal Hospital
Whipps Cross Hospital
Royal Devon and Exeter Hospital
Leicester Royal Infirmary
Derriford Hospital (Plymouth)
Press Reader. 17/05/2018. ‘Heart Trial Helps De-stress Josephine’ Available at: https://www.pressreader.com/uk/the-wokingham-paper/20180517/281857234187133
NIHR. 17/05/2018. ‘Berkshire woman staying healthy since taking part in heart monitor research trial’ Available at: https://www.nihr.ac.uk/news/berkshire-woman-staying-healthy-since-taking-part-in-heart-monitor-research-trial/8478
The Reading Chronicle. 16/05/2018. ‘Registrar praises innovative app which helps monitor heart rate’ Available at: http://www.readingchronicle.co.uk/news/16229340.Registrar_praises_innovative_app_which_helps_monitor_heartrate/
Director of EMERGE, Consultant, NRS Career Research Fellow & Honorary Reader in Emergency Medicine
10 Apr 2017 | Megan McGrath
EMERGE will soon begin recruitment to the new SNAP40 trial which will compare the new SNAP40 device with standard monitoring devices in the Emergency Department.Read more
EHA - Epidemiological analysis for the Hereditary Angioedema Disease is an international, multicentre, epidemiological study that aims to explore the feasibility of a new Dried Blood Spot (DBS) filtercard-based screening algorithm and thereby the prevalence of the Hereditary Angioedema.
EHA - Epidemiological analysis for the Hereditary Angioedema Disease
Diagnostics devices play an important part in the clinical assessment of a patient’s health and treatment. The purpose of the study is the evaluation of a new diagnostic platform developed by LumiraDx. The evaluation is focused around various biomarkers useful in the emergency settings.
Collection of venous and capillary blood samples for the evaluation of new diagnostic devices for cardiovascular conditions