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RATPAC

Start date:
Historic
End date:
June 2009
Co-ordinated by:
University of Sheffield

Randomised Assessment of Treatment using Panel Assay of Cardiac markers – a trial of rapid blood testing for acute chest pain in six NHS hospitals around the UK.

Aim

To evaluate the clinical effectiveness and cost-effectiveness of the most promising point-of-care cardiac marker panel currently used in the emergency department.

Trial Design

Multi centre randomised controlled trial of point of care markers vs standard care in patients with acute chest pain in the Emergency Department.

List of Publications – References

Goodacre SW, Bradburn M, Cross E, et al. The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart 2011;97:190–6.

Fitzgerald P, Goodacre SW, Cross E, Dixon S: Cost-effectiveness of point-of-care biomarker assessment for suspected myocardial infarction: the randomized assessment of treatment using panel Assay of cardiac markers (RATPAC) trial. Acad Emerg Med 2011; 18(5): 488-95.

Bradburn M, Goodacre SW, Fitzgerald P, Coats T, Gray A, Hassan T, Humphrey J, Kendall J, Smith J, Collinson P; RATPAC Research Team: Interhospital variation in the RATPAC trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers). Emerg Med J 2012; 29(3): 233-8.

Goodacre S, Bradburn M, Fitzgerald P Cross E, Collinson P, Gray A and Hall AS. The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Health Technology Assessment. (2011);15(23).

P Collinson, S Goodacre, D Gaze and A Gray. Very Early Diagnosis Of Chest Pain By Point Of Care Testing; Comparison Of The Diagnostic Efficiency Of A Panel Of Cardiac Biomarkers Compared To Troponin Measurement Alone In The Randomised Assessment Of Panel Assay Of Cardiac Markers (RATPAC) Trial. Heart. (2012);98:312-318.

Local PI

Professor Alasdair Gray

Director of EMERGE & Consultant in Emergency Medicine

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