Toggle menu

TPTIH

Start date:
August 2015
End date:
Predicted September 2017
Co-ordinated by:
The University of Nottingham

To establish genetic associations between patients with thiazide-induced hyponatraemia and patients taking a thiazide who did not develop hyponatraemia.

Eligibility criteria

Inclusion criteria:

  • Age 18-100 years
  • Have the capacity to give informed consent
  • Be taking a thiazide or thiazide-related diuretic unless in the non-thiazide control group
  • Plasma sodium concentration of less than 130 mM for cases and between 135 mM and 145 mM for controls

Local PI

Dr Ann Lockman

Consultant in Acute Medicine

Research Team

Julia Grahamslaw

Lead Research Nurse

Caroline Blackstock

AMU Senior Research Nurse

Bev Goldberg

AMU Senior Research Nurse

Rachel O'Brien

Lead Research Nurse

More EMERGE Trials

Identification and characterization of the clinical toxicology of novel psychoactive substances (NPS) by laboratory analysis of biological samples from recreational drug users.

Read more

IONA

Identification of Novel Psychoactive Substances (IONA)

Patients commonly present to the Emergency Department with epistaxsis (nose bleed). Standard first aid measures such as applying pressure can often stem bleeding however in more severe cases of epistaxsis further treatment is required.

Read more

NoPac

Novel Use of Tranexamic Acid to Reduce the Need for Nasal Packing

This study will investigate how we can help treat patients suffering from shock by the targeted use of specific fluids and medications. Shock is an acute medical condition in which the organs and tissues of the body are not receiving an adequate flow of blood. It is associated with a fall in blood pressure, a build-up in waste products and can result in serious organ damage and even death. We hope to improve our ability to treat shock by evaluating fluid management from the blood samples of a group of healthy volunteers.

Read more

The Prior Study

Calculating Osmotic Pressure in Healthy Patients