Dr Matt Reed

Director of EMERGE, Consultant, NRS Career Research Fellow & Honorary Reader in Emergency Medicine

Research Interests:
Syncope/transient loss of consciousness, Emergency Department organ donation, Cardiac arrest

Qualifications:
MA MB BCHIR MRCS FCEM MD

Twitter:
@mattreed73

Matt graduated from Cambridge University in 1997. He joined the South East Scotland Emergency Medicine Training Programme in 2002 and has been a Consultant in Emergency Medicine in Edinburgh since 2007. Matt is also an Honorary Reader with the Acute Care group of the University of Edinburgh.

After completing his Doctorate of Medicine thesis in 2009 on the risk stratification of syncope in the ED, Matt has continued research work in this area focusing on the use of biomarkers and ambulatory monitoring in syncope. He has published over 80 peer reviewed papers as well as numerous conference presentations and has personally been awarded over £950,000 in research contracts/grants in his career.

Matt is Deputy Director and Founder member of EMERGE, a member of the RCEM Research and Publication Committee, a member of the European Society of Cardiology Syncope Task Force, a module co-lead on the Queen Mary University of London MSc Emergency & Resuscitation medicine, chair of the Royal Infirmary of Edinburgh Hospital Transfusion Committee and immediate past chair of the Scottish Transfusion and Support in Trauma Group.

Key Publications

Reed MJ, Newby DE, Coull AJ, Jacques KG, Prescott RJ, Gray AJ. Risk stratification Of Syncope in the Emergency department: The ROSE study. JACC 2010: 55(8); 713-721. PMID: 20170806
Reed MJ, Mills NL, Weir CJ. Sensitive troponin assay predicts outcome in syncope. Emerg Med J. 2012; 29(12): 1001-3. PMID: 22962048
Reed MJ,Henderson SS, Newby DE, Gray AJ. One-year prognosis after syncope and the failure of the ROSE decision instrument to predict 1 year adverse events. Annals of Emergency Medicine 2011; Ann Emerg Med. 2011; 58(3): 250-6. PMID: 21288597
Thiruganasambandamoorthy V, Ramaekers R, Rahman MO, Stiell IG, Sikora L, Kelly S-L, Christ M, Claret P-G, Reed MJ.Prognostic Value of Cardiac Biomarkers in the Risk-Stratification of Syncope – A Systematic Review.Intern Emerg Med.2015; 10(8): 1003-14. PMID: 26498335
Brignole M, Moya A, Deharo J-C, de Lange F, Elliott P, Fedorowski A, Fanciulli A, Furlan R, Kenny RA, Martin A, Probst V, Reed MJ, Rice C, Sutton R, Ungar A, van Dijk G. 2018 ESC Guidelines for the diagnosis and management of syncope. European Heart Journal Epub 19 March 2018 doi:10.1093/eurheartj/ehy037
Brignole M, Moya A, Deharo J-C, de Lange F, Elliott P, Fedorowski A, Fanciulli A, Furlan R, Kenny RA, Martin A, Probst V, Reed MJ, Rice C, Sutton R, Ungar A, van Dijk G. Practical Instructions for the 2018 ESC Guidelines for the diagnosis and management of syncope. European Heart Journal Epub 19 March 2018 doi:10.1093/eurheartj/ehy071
Costantino G, Falavigna, G, Solbiati M, Casagranda I, Sun BC, Grossman SA, Quinn JV, Reed MJ, Ungar A, Montano N, Furlan R, Ippoliti R. Neural networks as a tool to predict syncope risk in the Emergency Department. EP Europace2017; 19(11): 1891-1895.PMID:28017935
Reed MJ, Gibson L, Dewar A, Short S, Black P, Clegg GR. Introduction of paramedic led Echo in Life Support into the pre-hospital environment: The PUCA study. Resuscitation2017; 112: 65–69. PMID: 27638418
Reed MJ, Glover A, Byrne L, Donald M, McMahon N, Hughes N, Littlewood NK, Garrett J, Innes C, McGarvey M, E Hazra E, Rawlinson PSM on behalf of the Scottish Transfusion and Laboratory Support in Trauma Group. Experience of implementing a National Code Red bleeding protocol in Scotland. Injury, Int. J. Care Injured2017; 48: 41–46. PMID: 27641222. Selected as one of the best 15 articles in the area of Transfusion Medicine research in the 2017 for the Transfusion Medicine Reviews Journal Club
Reed MJ, Kelly S-L, Beckwith H, Innes CJ, Manson L. Successful implementation of strategies to transform Emergency Department transfusion practice. BMJ Quality Improvement Reports 2013(2): doi:10.1136/bmjquality.u201055.w690
Reed MJ, Nimmo AF, McGee D, Manson L, Neffendorf AE, Moir L, Donaldson LS. Rotational thrombolelastometry produces potentially clinical useful results within 10 min in bleeding Emergency Department patients: the DEUCE study. Eur J Emerg Med. 2013; 20(3): 160-6
Sun BC, Costantino G, Barbic F, Bossi I, Casazza G, Dipaola F, McDermott F, Quinn J, Reed MJ, Sheldon RS, Solbiati M, Thiruganasambandamoorthy V, Krahn AD, Beach D, Bodemer N, Brignole M, Casagranda I, Duca P, Falavigna G, Ippoliti R, Montano N, Olshansky B, Raj SR, Ruwald MH, Shen W-K, Stiell I, Ungar A, van Dijk JG, van Dijk N, Wieling W, Furlan R. Priorities for Emergency Department Syncope Research. Annals of Emergency Medicine2014; 64(6): 649-55.PMID: 24882667
Sun BC, Thiruganasambandamoorthy V, Dela Cruz J, Abe H, Barbic F, Blanc J-J, Colivicchi F, Dipaola F, Furlan R,Costantino G, Grossman S, Hess E, Krahn A, Lipsitz L, Morillo C, Olshansky B, Quinn J, Raviele A, Reed MJ, Sarasin F, Satish R, Serrano L, Sheldon R, Thijs R, Ungar A, van Dijk G, van Dijk N. Standardized Reporting Guidelines for Emergency Department Syncope Risk Stratification Research. Academic Emergency Medicine2012; 19(6): 694-702. PMID: 22687184
Costantino G, Sun BC, Barbic F, Bossi I, Casazza G, Dipaola F, McDermott D, Quinn J, Reed MJ, Sheldon RS, Solbiati M, Thiruganasambandamoorthy V, Beach D, Bodemer N, Brignole M, Casagranda I, Del Rosso A, Duca P, Falavigna G, Grossman SA, Ippoliti R, Krahn AD, Montano N, Morillo CA, Olshansky B, Raj SR, Ruwald MH, Sarasin FP, Shen W-K, Stiell, IG, Ungar A, van Dijk JG, van Dijk N, Wieling W, Furlan R. Syncope clinical management in the Emergency Department: a consensus from the first international workshop on syncope risk stratification in the ED. Eur Heart J.2016; 37(19): 1493-8. PMID: 26242712

Grant Awarded

British Heart Foundation. The IPED (Investigation of Palpitations in the ED) study: Randomised controlled trial of the use of a smart phone based event recorder versus standard care for patients presenting to the Emergency Department with palpitations and pre-syncope. (£21,347). Grant holder; Chief Investigator 2017 (12 months)
Chief Scientist Office Research Grant. What is the best brain imaging strategy for patients with suspected minor stroke or transient ischaemic attack (TIA)?(£372,494), Co-applicant; Co-Investigator 2017 (30 months)
Small Business Research Initiative (SBRI). SNAP40-ED. Detection of physiological deterioration by the SNAP40 wearable device compared to standard monitoring devices in the Emergency Department. (£167,479), Grant holder; Chief Investigator 2017 (12 months)
Edinburgh and Lothians Grants Programme. A double blind randomised placebo controlled trial of topical Aloe Vera Gel in Emergency Department patients presenting with simple traumatic wounds (The ALOE study): (£20,000), Grant holder; Chief Investigator2016 (24 months) (Completed)
Chest, Heart and Stroke Scotland. Randomised control trial of a smart phone based event recorder for patients presenting to the Emergency Department with palpitations and pre-syncope – The IPED (Investigation of Palpitations in the ED) study. (£23,056), Grant holder; Chief Investigator 2015 (18 months)
Royal College of Emergency Medicine. A double blind randomised placebo controlled trial of topical Aloe Vera Gel in Emergency Department patients presenting with simple traumatic wounds (The ALOE study): (£5,700), Grant holder; Chief Investigator 2015 (24 months) (Completed)
Chest, Heart and Stroke Scotland. Diagnostic yield of an ambulatory patch monitor in Emergency Department syncope patients unexplained after Emergency Department evaluation – a pilot study (PATCH-ED) (£4,950), Grant holder; Chief Investigator 2015 (24 months) (Completed)
Edinburgh and Lothians Grants Programme. The Emergency Medicine Annotated Bioresource consortium (EM-ABC): A pilot and feasibility programme (£37,212), Grant holder; Chief Investigator 2014 (Completed)
Resuscitation Council UK. Introduction of paramedic led Echo in Life Support (ELS) into the pre-hospital environment (£19,718), Grant holder; Chief Investigator 2013 (Completed)
SNBTS. Is Rotational Thromboelastometry (ROTEM) useful to detect Occult Coagulopathy in the Emergency Department? (£6,624), Grant holder; Chief Investigator 2010 (Completed)
Chief Scientist Office Small Grant CZG/2/444 – Serial Brain Natriuretic Peptide (BNP) measurement in syncope. (£3,525): Final report graded Satisfactory, Grant holder; Chief Investigator 2009 (Completed)
CEM Research Committee and the BAEM Clinical Effectives Committee Research Grant – Prediction of Risk in Syncope using Electrocardiograph characteristics: a PILOT study (£1,721), Grant holder; Chief Investigator 2007 (Completed)
Chief Scientist Office Clinical Academic Training Fellowship CAF/06/0, Scottish Executive Health Department. Risk stratification Of Syncope in the Emergency department (£115,566). Final report graded Excellent, Grant holder; Chief Investigator 2006 (Completed)

Teaching Interests

Critical appraisal of the scientific literature
Advanced trauma life support (ATLS)
Advanced Life Support (ALS)
Emergency Ultrasound
Supervising students undertaking

Professional Activities

Founding member USHER Institute Acute Care Research Group
Module Co-Lead PGCIP/MSc Emergency & Resuscitation medicine (Queen Mary University of London)
Chair Royal Infirmary of Edinburgh Hospital Transfusion Committee
Member Scottish Transfusion and Support in Trauma Group
Chair Emergency Department Blood Group
Director Edinburgh NEMUS Ultrasound courses
Member NHS Lothian Hospital Transfusion Committee
Member of European Society of Cardiology Syncope Task Force
Member Royal College of Emergency Medicine Research & Publication Committee

Trials

Trauma remains a major cause of mortality and morbidity. 10% of blunt force trauma patients admitted to a major trauma centre will have sustained one or more fractured ribs, which may cause significant pain and problems with breathing.

To establish the outcome of rib fractures and their treatments it is important to know what to measure, and how to measure this accurately. A patient reported outcome measure (PROM) is a questionnaire used to measure patient reported outcomes, to show how the patient is doing from their perspective.

Whilst there is ongoing interest in surgery to fix broken ribs, there is no PROM specifically designed for patients with broken ribs following chest trauma. Therefore, it is not clear whether the symptoms that are most important to these patients are being represented by the current outcome measures. This study aims to create a PROM specific to rib fracture patients to give us a better understanding of whether a new treatment actually makes a difference to the patient’s recovery.

The 1st part of the study involves asking patients with rib fractures to help design a new PROM. This will be conducted through focus groups at a site in Nottingham. The 2nd part of the study entails field testing, whereby patients with rib fractures will be asked to test this new PROM. This will be conducted across multiple secondary care settings in the UK, including the Royal Infirmary of Edinburgh. The study is expected to run for approximately 2 years, with recruitment targets of 50 patients for the PROM Creation phase and 250 for the Field Testing phase.

Prospective multicentre observational study conducted over one calendar month in 2019, with the aim of describing the epidemiology of non-trauma related headache in adults presenting to emergency departments including investigations, treatments and outcome.

This will include adult patients presenting to the ED with non-trauma-related headache as their primary complaint.

EHA - Epidemiological analysis for the Hereditary Angioedema Disease is an international, multicentre, epidemiological study that aims to explore the feasibility of a new Dried Blood Spot (DBS) filtercard-based screening algorithm and thereby the prevalence of the Hereditary Angioedema.

Dr Matt Reed

Key Publications

Grant Awarded

Teaching Interests

Professional Activities

Trials

COVID BreathSpec

PROM OCTS

HEAD Study

BreathSpec study

EHA Study

SECUre – A Multicentre Survey of the Safety of Emergency Care in UK Emergency Departments

BRAINED Study

ATTEST2 Trial

SNAP40 Study

NoPac Trial

IPED Trial

E-FIT1 Trial

DEUCE

PREFER

ROSE

AHEAD

EMERGE Biobank

EURODEM

PATCH-ED

TICH 2 Trial

ENCEPH UK Study

Blood Project

Code Red

Halt-It Trial

Related news

Exciting new trial: SNAP40

The Beats That My Heart Skipped

IPED goes large!

Severe Traumatic Haemorrhage – Page Research Nurses on 4116

Matt and Louise at the 2015 Resuscitation Symposium

PATCH-ED IS HERE

#WhyWeDoResearch