AHEAD
Start date:Historic End date:
March 2013 Co-ordinated by:
University of Sheffield
Monitoring anticoagulated patients who suffer head injury
Aim
- Identify the outcomes of anticoagulated patients attending the ED following head injury
- Collect prospective data to enable the risk of serious intracranial pathology to be calculated for this patient group (defined in this study as death or neurosurgery resulting from the initial injury, or Computerised Tomography (CT) scan finding mandating admission or readmission to hospital)
- Use baseline and follow up data to identify useful predictors of adverse outcome in this patient group
- Evaluate the cost-effectiveness of different clinical management strategies for this patient group
- Identify important factors in the clinical consultation and assessment process following head injury that may be useful as a diagnostic tool.
Trial Design
Prospective, multi-centre, pragmatic observational cohort study
Chief Investigator
Professor Suzanne Mason
Local PI
Dr. Matt Reed
List of Publications – references
Mason S, Kuczawski M, Teare M, Stevenson M, Holmes M, Ramlakhan S, Goodacr S, Morris F, Harper R: THE AHEAD STUDY: MANAGING ANTICOAGULATED PATIENTS WHO SUFFER HEAD INJURY. Emergency Medicine Journal (2014);31:775
Local PI
Dr Matt Reed
Director of EMERGE, Consultant, NRS Career Research Fellow & Honorary Reader in Emergency Medicine
More EMERGE Trials
DASH Trial
DASH is a randomised clinical trial investigating a treatment to reverse the effects of blood-thinning medications.
Assisting in identifying patients with Humeral shaft fractures in the ED by screening.
Giving patient information sheets to introduce the study, so patient has had adequate time to read and make decision about going into the trial before going to the fracture clinic.
HU-FIX Trial
Diagnostics devices play an important part in the clinical assessment of a patient’s health and treatment. The purpose of the study is the evaluation of a new diagnostic platform developed by LumiraDx. The evaluation is focused around various biomarkers useful in the emergency settings.
NOVEL Study
Collection of venous and capillary blood samples for the evaluation of new diagnostic devices for cardiovascular conditions