Time and Motion
Start date:unknown End date:
February 2015 Co-ordinated by:
Amy Dunn, Rachel O’Brien
To explore the time taken for research nurses to recruit patients in an Emergency Department (ED) setting. To identify any challenges to recruitment and to ascertain methods to optimise participant recruitment.
Trial Design
Observational
List of Publications – References
Poster submissions
Lothian R&D Conference – 6th March 2015
RCN Annual International Research Conference – 20th – 22nd April 2015 – Winner for Best Poster
Scottish Emergency Medicine Clinical Meeting – 19th May 2015
Research Team
Rachel O'Brien
Lead Research Nurse
More EMERGE Trials
ATTEST2 Trial
Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST 2)
People who develop an Acute Kidney Injury (AKI) often have a poor prognosis and many go on to develop chronic kidney disease (CKD). The recognition that AKI and CKD are linked is recent and the molecular pathways that control the transition from acute injury to chronic disease are not well defined. Currently there are no specific treatments that reduce the risk of progressing to CKD after AKI.
Preliminary investigations (not yet published) suggest that AKI causes sustained activation of the endothelin (ET) system to the long-term detriment of renal and systemic haemodynamic function. These pilot data form the basis of our project that seeks to determine whether the ET system is active in patients with AKI and, thus, represents a potential target for therapeutic intervention.
KRAKIL aims to recruit altogether 100 patients from across the emergency department, acute medical unit and inpatient wards at the Royal Infirmary. 50 of which with AKI’s and 50 matched controls with normal kidney function. We will monitor their bloods and urine for 90 days and compare the data from between the two groups.