Below are details of all current trials at EMERGE. Either click the area you are interested to see relevant studies or scroll through all our work.
If there is a study you’re interested in that isn’t listed here or you’d like to discuss a study with us then please get in touch. If you’re interested in a commercial collaboration and EMERGE evaluating something for you the please visit our Commercial Collaboration page.
Previous Cardiovascular Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
| 3CPO | 3CPO Trial | A randomised controlled trial of continuous positive airway pressure (CPAP) vs non invasive ventilation (NIV) vs standard therapy for acute pulmonary odema (ACPO) | NIHR HTA | Professor Alasdair Gray | Moyra Masson | Closed to Recruitment |
![]() | Garfield-VTE Study | Global Anticoagulant Registry in the FIELD observing treatment and outcomes in patients with treated acute Venous Thromboembolic Events in the real world | Bayer AG | Dr. Ann Lockman | Caroline Blackstock | Closed to Recruitment |
![]() | HighSTEACS | HighSTEACS is a randomised controlled trial, across 10 hospitals in NHS Lothian and NHS Greater Glasgow & Clyde, assessing patient outcomes before and after the implementation of high sensitivity Troponin assay | BHF | Professor Alasdair Gray | Rachel O’Brien | Closed to Recruitment |
| HighSTEACS Bioresource | HighSTEACS Bioresource | Evaluating the kinetics of cardiac biomarkers after ST-segment Elevation myocardial infarction | BHF | Professor Alasdair Gray | Rachel O’Brien | Closed to Recruitment |
![]() | IPED Trial | Randomised controlled Trial using smart phone based event recorder technology versus standard care in palpatations or pre-syncope | CHSS / BHF | Dr Matt Reed | Mia Paderanga | Closed to Recruitment |
![]() | IPED implementation study | Real-world clinical implementation of a smartphone-based event recorder in the ED for patients with palpitation | n/a | Dr Matt Reed | Dr Julia Cullen | Closed to Recruitment |
| PRECISE-CTCA | PRECISE-CTCA Trial | troPonin within the noRmal refEerenCe range to risk Stratify patients with acute chEst pain for Computed Tomography Coronary Angiography | British Heart Foundation | Dr Ken Lee | Rachel O’Brien | Closed to Recruitment |
![]() | PREFER | Prefer in VTE Prevention of Thromboembolic Events – European Registry in Venous Thromboembolism | EUSEM | Dr Matt Reed | Rachel O’Brien & Julia Grahamslaw | Closed to Recruitment |
![]() | RAPID-CTCA Trial | Evaluate role of early CT Coronary Angiography in the evaluation, intervention and outcome of patients presenting to the Emergency Department with suspected or confirmed Acute Coronary Syndrome | BHF | Professor Alasdair Gray | Rachel O’Brien | Closed to Recruitment |
![]() | RATPAC | Randomised Assessment of Treatment using Panel Assay of Cardiac markers | NIHR HTA | Professor Alasdair Gray | Judy Coyle | Closed to Recruitment |
![]() | Relax 2 Trial | A multicenter, randomised, double-blind, placebo-controlled phase IIIb study to evaluate the efficacy, safety and tolerability of Serelaxin when added to standard therapy in acute heart failure patients (CRLXA). | Novartis | Professor Alasdair Gray | Julia Grahamslaw | Closed to Recruitment |
![]() | DAShED | The DAShED (Diagnosis of Acute Aortic Syndrome in the ED) study | RCEM | Dr Rachel McLatchie | Rachel O’Brien | Closed - submitted for publication. |
| ROSE | ROSE | Risk Stratification Of Syncope in the Emergency department | CSO | Dr Matt Reed | Dr Matt Reed | Closed to Recruitment |
| ACUTE | ACUTE | A mechanistic study of intravenous thiamine for acute heart failure | Medical Research Council | Professor Michael Eddleston& Professor Matt Reed | Caroline Blackstock | Closed to Recruitment |
Previous Stroke and Neurosurgery Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
| AHEAD | AHEAD | Monitoring anticoagulated patients who suffer head injury | NIHR Research for Patient Benefit Programme | Dr Matt Reed | Jan Gilchrist | Closed to Recruitment |
| AXIOMATIC-SSP | AXIOMATIC-SSP | Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute | Bristol-Myers Squibb | Dr Neil Hunter | Michelle Coakley | Closed to Recruitment |
| BRAINED Study | BRAINED Study | Blood samples will be assessed using infrared spectroscopy as part of a project looking at tumour biomarkers to ascertain whether people most at risk of having a brain tumour can be correctly identified | Dr Paul Brennan | Polly Black | Closed to Recruitment | |
![]() | DASH Trial | DASH is a randomised clinical trial investigating a treatment to reverse the effects of blood-thinning medications. | NIHR | Professor Rustam Al-Shahi Salman | Michelle Coakley | Closed to Recruitment |
| ETNA | ETNA | Edinburgh Transient and Neurological attack: A Cohort Study | Chief Scientist’s Office | Dr Will Whiteley | Allan MacRaild | Closed to Recruitment |
![]() | HeadOn Study | Delivery of digital cognitive behaviour therpy following concusion: HeadOn Feasibility Study | NIHR Brain Injury, MedTech Co-operative, Seedcorn Funding Competition | Aimun Jamjoom/Dr Matt Reed | Alison Grant | Closed to Recruitment |
![]() | Laci-2 | Assessment of safety and efficacy of cilostazol and isosorbide mononitrate to | British Heart Foundation | Professor Joanna Wardlaw | Allan MacRaild | Closed to Recruitment |
![]() | LINCH-PIN | Lothian study of INtraCerebral Haemorrhage Pathology, Imaging & Neurological outcome | UK Medical Research Council and The Stroke Association | Dr Neshika Samarasekera | Allan MacRaild | Closed to Recruitment |
| MRI in Acute Stroke | MRI in Acute Stroke | MRI in Acute Stroke Timing | Springboard Grant from North Bristol Trust and Dunhill Medical Trust | Allan MacRaild | Closed to Recruitment | |
![]() | PitSTOP | To determine the prevalence of anterior pituitary gland dysfunction in traumatic brain injury in Scotland | Dr John Emelifeonwu | Julia Grahamslaw | Closed to Recruitment | |
![]() | PRECIOUS | A clinical trial to look at PREvention of Complications to | European Union’s Horizon 2020 Research and Innovation | Professor Malcolm MacLeod | Jessica Teasdale | Closed to Recruitment |
![]() | R4VAD | Rates, Risks and Routes to Reduce Vascular Dementia | Stroke Association, Alzheimer’s Society, and British Heart Foundation | Professor Joanna Wardlaw | Rachel Sutherland | Closed to Recruitment |
| TICH-2 Trial | TICH 2 Trial | Tranexamic Acid for Hyperacute Primary IntraCerebral Haemorrhage | NIHR | Professor Rustam Al-Shahi Salman | Allan MacRaild | Closed to Recruitment |
![]() | TREAT-SVD | EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases | European Union | Dr Joanna Wardlaw | Dr Joanna Wardlaw | Closed to Recruitment |
![]() | TRIDENT | Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial | National Health and Medical Research Council (NHMRC) of Australia | Dr Neshika Samarasekera | Allan MacRaild | Closed to Recruitment |
![]() | ATTEST2 Trial | Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis | Stroke Association & British Heart Foundation | Dr William Whitely | Allan MacRaild | Closed to Recruitment |
| BRAINED- TBI | BRAINED – TBI | Using Fourier Transform Infrared Spectrotroscopy for Earlier Diagnosis and Rapid Stratification of Patients with a Traumatic Brain Injury | NIHR Brain Injury MedTech Co-operative Seedcorn Funding Competition | Dr Paul Brennan | Sarah Risbridger | Closed to Recruitment |
![]() | CARE | Cavernomas A Randomised Effectiveness (CARE) pilot trial, to address the effectiveness of active treatment (with neurosurgery or stereotactic radiosurgery) versus conservative management in people with symptomatic brain cavernoma | NIHR | Mr Ioannis Fouyas | Allan MacRaild | Closed to Recruitment |
![]() | DENS | Duration of External Neck Stabilisation following odontoid fracture in older or frail adults: a randomised controlled trial of collar versus no collar | NIHR HTA | Dr Paul Brennan/Professor Matt Reed | Anuka Boldbaatar | Closed to Recruitment |
![]() | INFERENCE | IdentificatioN oF biomarkErs foR Early diagNosis of CancEr | Innovate UK | Dr Paul Brennan | Sarah Risbridger | Closed to Recruitment |
![]() | OPTIMAS | OPtimal TIMing of Anticoagulation after acute ischaemic Stroke: a randomised controlled trial | British Heart Foundation | Dr Fergus Dougal | Sarah Risbridger | Closed to Recruitment |
![]() | PROHIBIT-ICH | Prevention Of Hypertensive Injury to the Brain by Intensive Treatment after IntraCerebral Haemorrhage: a pilot randomised trial of home telemetry-guidedtreatment | Stroke Association | Neshika Samarasekera | Allan MacRaild | Closed to Recruitment |
| Shared Stroke Decisions | Shared Stroke Decisions | Development and implementation of Realistic Medicine for severe stroke through Shared Decision Making | Edinburgh and Lothian Health Foundation | Professor Gillian Mead | Sarah Risbridger | Closed to Recruitment |
| Can-SCAHn | Can-SCAHn | Selective neuroimaging for head-injured emergency patients who take anticoagulant medication. | Canadian Institutes of Health Research | Professor Matt Reed | Julia Grahamslaw | Closed to Recruitment |
| BRAINED3 | BRAINED3 | Assessing the performance of Infrared blood-based spectroscopy technology and its ability to identify patients suffering from non-specific symptoms who have a brain cancer. | Dr Paul Brennan | Shona McDonald | Closed to Recruitment | |
![]() | BRAIN MATRIX | A BRitish feasibility study of molecular stratification and targeted therapy to optimize the clinical mAnagement of patieNts with glioMA by enhancing clinical ouTcomes, Reducing avoidable toXicity, improving management of post-operative residual & recurrent disease and improving survivorship | The Brain Tumour Charity and Genomics England | Dr Paul Brennan | Allan MacRaild | Closed to Recruitment |
![]() | Feasibility Study of the CT Clock Tool for Estimating Onset Time of Ischaemic Stroke | Feasibility Study of the CT Clock Tool for Estimating Onset Time of Ischaemic Stroke. Our proposed CT Clock Tool method for estimating the time of stroke onset (and thus clarifying individual patient eligibility for effective treatment) is significantly simpler to use in the acute setting than the advanced methods currently available (CT perfusion or MRI) | MRC (Medical Research Council) Impact Acceleration Account (IAA) | Dr Grant Mair | Allan MacRaild | Closed to Recruitment |
| OCEANIC STROKE | Oceanic Stroke | Phase 3 study to investigate the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) compared with placebo in participants after an acute non-cardioembolic ischemic stroke or high-risk TIA | Bayer AG | Neil Hunter | Sarah Risbridger | Closed to Recruitment |
| PreSize | PreSize | Real-World Performance Evaluation of PreSize Neurovascular Medical Software in a Clinical Setting | Oxford Heartbeat | Dr Jonny Downer | Sarah Risbridger | Closed to Recruitment |
| TREAT | TREAT | Trenza Embolization Device for Intrasaccular Aneurysm Treatment | STRYKER | Dr Jonny Downer | Allan MacRaild | Closed to Recruitment |
![]() | TRIDENT | Triple therapy prevention of Recurrent Intracerebral Disease EveNts Trial | Neshika Samarasekera | Allan MacRaild | Closed to Recruitment | |
| IMPACT | IMPACT | International Post Market Product Surveillance Study of Intracranial Aneurysms Treated with an Endovascular Approach | STRYKER | Dr Jonny Downer | Allan MacRaild | Closed to Recruitment |
Previous Toxicology Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
| MUP | Minimal Unit Pricing Study (MUP) | Measure the effect of Minimum Unit Pricing in Emergency Care Settings | NIHR | Dr Michelle Open | Emma Moatt | Closed to Recruitment |
![]() | The POP Trial | Professor James Dear | Allan MacRaild | Closed to Recruitment | ||
![]() | SNAP Trial | Scottish and Newcastle Anti-emetic Pre-treatment for Paracetamol Poisoning Study | Professor James Dear | Judy Coyle | Closed to Recruitment | |
| IONA | IONA | Identification Of Novel psychoActive substances | NIHR portfolio | Professor Michael Eddleston | Caroline Blackstock | Closed to Recruitment |
![]() | MAPP2 Study | The Markers and Paracetamol Poisoning Study 2 | Rosetrees Trust and Kidney Research UK | Professor James Dear | Caroline Blackstock | Closed to Recruitment |
| TIPSS | TIPSS | This trial aims to determine where in the body sulbutiamine/benfotiamine is converted to thiamine. | Medical Research Council (MRC) (Confidence in Concept Fund) | Professor Michael Eddleston | Anna Miell | Closed to Recruitment |
| Thiamine in CSF | Thiamine in CSF | This study aims to compare several forms of thiamine by testing the absorption into the blood and cerebrospinal fluid (CSF) at different time points after taking a dose | Professor Michael Eddleston | Anna Miell | Closed to Recruitment |
Previous Blood Project Group Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | National Code Red Audit | The aim of this audit is to monitor and optimise the transfusion support given to patients following major trauma in Scotland. | SNBTS | Professor Matt Reed | Professor Matt Reed | Closed to Recruitment |
![]() | DEUCE | Is Rotational Thromboelastometry (ROTEM) useful to detect Occult Coagulopathy in the Emergency Department? | SNBTS | Dr Matt Reed | Allan MacRaild | Closed to Recruitment |
| E-FIT1 | E-FIT1 Trial | RCT or fibrinogen concentrate within 45 minutes of admission to hospital in adult trauma patients with severe bleeding | CSL Behring | Dr Matt Reed | Bernadette Gallagher | Closed to Recruitment |
![]() | Halt-It Trial | Tranexamic acid for the treatment of gastrointestinal haemorrhage: an international randomised, double blind placebo controlled trial | NIHR HTA | Dr Matt Reed | Julia Grahamslaw | Closed to Recruitment |
![]() | National Code Red Audit | The aim of this audit is to monitor and optimise the transfusion support given to patients following major trauma in Scotland. | SNBTS | Dr Matt Reed | Dr Matt Reed | Closed to Recruitment |
![]() | NoPac Trial | Tranexamic acid for the treatment of epistaxis: a randomised, double blind placebo controlled trial | NIHR RfPB | Dr Matt Reed | Polly Black | Closed to Recruitment |
| ROTEM | Rotem in ED | Single centre, prospective, observational Emergency Department based study of trauma patients who undergo ROTEM testing | RCEM | Dr Matt Reed | Dr Matt Reed | Closed to Recruitment |
| TRIGGER | TRIGGER | Transfusion in Gastrointestinal Bleeding | NHS Blood and Transplant Research and Development. | Professor Alasdair Gray | Rachel O’Brien | Closed to Recruitment |
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | BreathSpec-COVID | Breath analysis for the detection of COVID19 | RCEM | Dr Matt Reed | Rachel O’Brien | Closed to Recruitment |
![]() | CERA | Understand the evolving and cumulative effects of working during the COVID-19 outbreak on the psychological health of those physicians working in the emergency care settings across the UK | Emily Godden & Emma Moatt | Closed to Recruitment | ||
| COV_002 Vaccine Trial | COV_002 Vaccine Trial | To test a new vaccine, ChAdOx1 nCoV-19, against COVID-19 in healthy volunteers | Rachel O’Brien | Closed to Recruitment | ||
![]() | FALCON | Facilitating AcceLerated Clinical evaluation Of Novel diagnostic tests for COVID-19 | NIHR, Asthma UK & British Lung Foundation | Dr. Rachel McLatchie | Caroline Blackstock | Closed to Recruitment |
![]() | ISARIC4C | Clinical Characterisation Protocol for Severe Emerging | MRC, Wellcome Trust, SPRINT-SARI NIHR Health Protection Research Unit (HPRU) in Respiratory Infection, HPRU in Emerging and Zoonotic Infections | Dr Kenneth Baillie | Caroline Blackstock | Closed to Recruitment |
| PAN-ED | PAN-ED | Emily Godden & Emma Moatt | Emily Godden & Emma Moatt | Closed to Recruitment | ||
![]() | PRIEST | Evaluate current triage methods used to determine if a patient with suspected COVID-19 is to be admitted to hospital or not and whether or not they should be admitted to ICU/HDU | Polly Black | Closed to Recruitment | ||
![]() | RECOVERY | Randomised Evaluation of COVID-19 Therapy | Dr. Alasdair Gray | Allan MacRaild | Closed to Recruitment | |
![]() | SIREN | The impact of detectable anti SARS-COV2 antibody on the incidence of COVID-19 in healthcare workers | Dr. Alasdair Gray | Allan MacRaild | Closed to Recruitment |
Previous Trauma, Surgical and Orthopaedics Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | HU-FIX Trial | A trial of operative versus conservative management in humeral shaft fractures | Closed to Recruitment | |||
![]() | PROM OCTS | The creation and field testing of a new rib fracture specific patient reported outcome measure | AOUK&I/NIHR HTA ORiF | Dr Matt Reed | Nicky Freeman | Closed to Recruitment |
![]() | RELIEF | The Randomised Evaluation of early topical Lidocaine patches In Elderly patients admitted to hospital with rib Fractures (RELIEF): feasibility trial | North Bristol NHS Trust | Dr. Edward Carlton | Fiona McCurrach | Closed to Recruitment |
| RACER | RACER | Robotic Arthroplasty: a Clinical and cost Effectiveness Randomised controlled trial | Ms Chloe Scott | Victoria Minnis | Closed to Recruitment |
Previous Sepsis Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | ABC SEPSIS | Feasibility of 5% Albumin compared with Balanced Crystalloid, as intravenous | The Jon Moulton Charity Trust | Professor Alasdair Gray | Julia Grahamslaw | Closed to Recruitment |
![]() | CVLA Study | Capillary and Venous Lactate Agreement – a pilot observational study | Dr Dip Datta | Julia Grahamslaw | Closed to Recruitment | |
![]() | ExPRES SEPSIS | To derive a biomarker to allow the identification of patients with confirmed sepsis, and risk stratify patients at risk of developing severe sepsis | Professor Tim Walsh | Julia Grahamslaw | Closed to Recruitment | |
![]() | LAVAS Study | Lactate, Arterial and Venous Agreement in Sepsis | Dr Dip Datta | Julia Grahamslaw | Closed to Recruitment | |
![]() | MIS-ABC Sepsis | Mechanistic Inflammatory Sub-study | The Royal College of Emergency Medicine | Dr. Jack Cafferkey | Julia Grahamslaw | Closed to Recruitment |
Previous Paediatric Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
| EcLiPSE | EcLiPSE Trial | Comparing intravenous levetiracetam to intravenous phenytoin for the treatment of convulsive status epilepticus (CSE) in children, young people and young adults | NIHR HTA | Dr Jen Browning | Julia Grahamslaw | Closed to Recruitment |
![]() | BRONCHSTART2 | The Impact of the COVID-19 Pandemic on the Timing, Age and Severity of Respiratory Syncytial Virus (RSV) Emergency Presentations, a Multi Centre Prospective Observational Cohort Study Extension. | PERUKI and RESCEU | Thomas Williams | Ashleigh Hegan | Closed to Recruitment |
| Button Batteries | Button Batteries | The unintentional ingestion, inhalation or insertion of button batteries in children requiring removal or attempted removal | Sir Peter Tizard Research Bursary | Dr Suvradeep Basu | Ashleigh Hegan | Completing Follow Up |
![]() | INFORM | Point of Care device for the detection of Influenza A/B, Respiratory Syncytial Virus (RSV) & SARS-COV-2 Virus | LumiraDX | Dr. Jen Browning | Caroline Blackstock | Closed to Recruitment |
![]() | MAGNETIC | A prospective surveillance study of magnetic ingestion in children | N/A | Professor Nigel Hall | Ashleigh Hegan | Closed to Recruitment |
![]() | MAST | Pharmacological Management of Seizures post Traumatic Brain Injury. | NIHR | Dr Jay Shetty | Caroline Blackstock | Closed to Recruitment |
![]() | FIDO | Validating clinical decision aids for the assessment and management of febrile infants presenting to emergency care in the UK and Ireland. | Royal College of Emergency Medicine Doctoral Fellowship | Dr Thomas Waterfield | Caroline Blackstock | Closed to Recruitment |
Other Previous Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | Time and Motion | To explore the time taken for research nurses to recruit patients in an Emergency Department (ED) setting | n/a | Rachel O’Brien& Polly Black | Rachel O’Brien& Polly Black | Closed to Recruitment |
![]() | 3MG Trial | A randomised trial of intravenous or nebulised magnesium sulphate versus placebo for acute severe asthma | NIHR HTA | Professor Alasdair Gray | Moyra Masson | Closed to Recruitment |
![]() | 4AT Study | To determine the diagnostic accuracy of the 4AT for delirium versus the reference standard of a DSM-IV diagnosis | Closed to Recruitment | |||
![]() | EURODEM | The European Dyspnoea survey in the Emergency Departments | EUSEM | Dr Matt Reed | Rachel O’Brien | Closed to Recruitment |
| POEM | Assess the adequacy of pain management in patients presenting to the ED with confirmed long bone fracture and/or dislocation isolated to a proximal or distal limb | Closed to Recruitment | ||||
| First 'First Responder' | First “First Responder” Study | Provide the first in-depth look into the experience of the OHCA bystander responder | Joel Symonds | Closed to Recruitment | ||
| ENCEPH UK Study | ENCEPH UK Study | To produce a predictive tool for HSV encephalitis based on the early clinical features, by comparing the clinical features of those with and without HSV encephalitis | NIHR Programme for Applied Research | Dr Matt Reed | Julia Grahamslaw | Closed to Recruitment |
![]() | COPS | Dr Frank Prior | Dr Frank Prior | Closed to Recruitment | ||
![]() | The Prior Study | Plot the Membrane Osmotic Pressure (MOP) and Mean arterial pressure (MAP) of healthy participants onto a chart that has been created from previous work | Dr Frank Prior | Dr Frank Prior | Closed to Recruitment | |
| The STRETCHED Study | STRETCHED | Subsequent healthcare resource utilisation in patients discharge from Emergency Care after a presentation with acute severe headache – a feasibility study with hypothesis generating mixed methodsanalysis | Professor Matt Reed | Alison Grant | Closed to Recruitment | |
![]() | CoSTED | Cessation Of Smoking Trial in the Emergency Department | Norfolk and Norwich University Hospitals NHS Foundation Trust (NNUH) | Professor Alasdair Gray | Anna Miell | Closed to Recruitment |
![]() | CoMiTED | Conservative Management in Traumatic Pneumothoraces in the Emergency Department (CoMiTED) | NIHR-HTA | Professor Edward Carlton/Dr Lyle Moncur | Nicky Freeman | Closed to Recruitment |
| FORCE:SEE | FORCE:SEE | Frailty and Outcomes Record in Clinical Environments: probable Sarcopenia, geriatric Evaluation, and Events | Dr Alixe Kilgour | Victoria Minnis | Closed to Recruitment | |
| UPDATE-ED | UPDATE-ED | Understanding Psychological Distress and Therapeutic Environment in the Emergency Department (The UPDATE-ED Study) | Anna Miell | Closed to Recruitment | ||
| POS-ARI-ER | POS-ARI-ER | The POS-ARI-ER study is a multicentre, Perpetual Observational Study of patients with suspected Acute Respiratory Infections presenting via Emergency Rooms and other acute hospital care settings. | European Commission H2020 | Dr Jon Carter | Sheryl Page | Closed to Recruitment |
Innovation Studies
Previous Biomarker Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | AKI in LC Study | A study of AKI in hospital patients | Fiona Gifford | Caroline Blackstock | Closed to Recruitment | |
![]() | EHA Study | A diagnostic screening study for hereditary angioedema in the ED | Centrogene | Dr Matt Reed | Fiona McCurrach | Closed to Recruitment |
![]() | EMBOL1 Study | A Performance Evaluation of The LumiraDX Point of Care D-DIMER | LumiraDX | Professor Alasdair Gray | Caroline Blackstock | Closed to Recruitment |
![]() | NOVEL Study | Collection of Venous and Capillary Blood Samples for the Development of New Diagnostic Devices for Cardiovascular Conditions | LumiraDX | Professor Alasdair Gray | Anna Miell | Closed to Recruitment |
![]() | REACT Study | A Performance Evaluation of The LumiraDX Point of Care CRP Assay | LumiraDX | Professor Alasdair Gray | Caroline Blackstock | Closed to Recruitment |
| TPTIH | TPTIH | To establish genetic associations between patients with thiazide-induced hyponatraemia and patients taking a thiazide who did not develop hyponatraemia | Ann Lockman | Caroline Blackstock | Closed to Recruitment | |
| Biomarkers for Acute Aortic Syndrome | Biomarkers for Acute Aortic Syndrome | We aim to identify genetic biomarkers of acute aortic syndrome as a potential diagnostic and prognostic tool. Detecting biomarkers which can help identify and differentiate acute/unstable states of aortic (& other vascular) disease as compared to the chronic phase of disease and those without arterial disease would be of clinical benefit. | Tim Aitman, Andrew Tambyraja | Ellise Clarke | Closed to Recruitment | |
| PERFORM TSIX | PERFORM-TSIX | Clinical Performance of Elecsys® Troponin T hs Gen 6 in Subjects with Symptoms of Acute Coronary Syndrome. The purpose of this research study is to evaluate the performance of the investigational diagnostic test which may help doctors diagnose heart attacks faster and more accurately than they can today. | Roche | Professor Richard Body/ Dr Stephen Lynch | Caroline Blackstock | Closed to Recruitment |
Previous Medical Wearable Device Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | PATCH-ED | Diagnostic yield of an ambulatory patch monitor in Emergency Department syncope patients unexplained after Emergency Department evaluation | Chest, Heart and Stroke Scotland | Dr Matt Reed | Kirsty Simpson | Closed to Recruitment |
![]() | RAMPP trial | Investigate the use of a pleural vent (rocket) versus standard care in patients with Primary Spontaneous Pnuemothorax in a randomised controlled trial | Medical Research Council and the National Institute for Health Research (UK) | Dr Marie-Clare Harris | Mia Paderanga | Closed to Recruitment |
Data Projects
Previous Data Science Studies
| Logo | Title | Description | Funding Body | Chief/Principal Investigator | Key Contact | Status |
|---|---|---|---|---|---|---|
![]() | Improving Multi-Morbidity Acute Care Using Data Analytics | SBRI: Improving Multi-Morbidity Acute Care Using Data Analytics | Health Innovation South East Scotland / Innovate UK | Naz Lone/Professor Matt Reed | Professor Matt Reed | Closed to Recruitment |
![]() | Improving Care through Data Driven Innovation | Multimorbidity and Emergency Healthcare Provision: Improving Care through Data Driven Innovation | Wellcome Trust ISSF3 | Naz Lone/Professor Matt Reed | Professor Matt Reed | Closed to Recruitment |



































































